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KMID : 1001920150570030211
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Journal of Korean Neurosurgical Society
2015 Volume.57 No. 3 p.211 ~ p.214
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A Malignant Transformation of a Spinal Epidural Mass from Ganglioneuroblastoma to Neuroblastoma
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Akcakaya Mehmet Osman
Bilgic Bilge
Aras Yavuz
Izgi Nail
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Abstract
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Ganglioneuromas are benign tumors. Surgical excision is the treatment of choice with very good prognosis. However, neuroblastomatous malignant transformation of ganglioneuromas was previously reported. We report a patient with spinal neuroblastoma recurrent from a ganglioneuroblastoma after disease free survival of 13 years. This is one of the rare examples of spinal neuroblastoma and to our knowledge the second case report with malignant transformation from a ganglioneuroblastoma or a ganglioneuroma. The present case is the only report in the literature with further genetic investigations.
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KEYWORD
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Ganglioneuroblastoma, Neuroblastoma, Malignant transformation, Spinal tumor
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